Shakhtar Donetsk vs RB Leipzig Prediction & Odds – Champions League Matchday 6

In-form Germans meet Ukraine side in Poland at 1:45 pm ET on Wednesday Shakhtar Donetsk won 4-1 in Leipzig in the opening game in Group F See the Shakhtar Donetsk vs RB Leipzig odds and best bets for UCL Matchday 6 Both teams can qualify for the last 16 of...

April 17, 2026 • 5:06 AM

In-form Germans meet Ukraine side in Poland at 1:45 pm ET on Wednesday

Shakhtar Donetsk won 4-1 in Leipzig in the opening game in Group F

See the Shakhtar Donetsk vs RB Leipzig odds and best bets for UCL Matchday 6

Both teams can qualify for the last 16 of the Champions League in Shakhtar Donetsk vs RB Leipzig on Wednesday.

In-form Leipzig can finish on top of Group F if they win and Real Madrid fail to beat Celtic.

Meanwhile, Shakhtar Donetsk could claim second place in the table with a victory. 

Although it would then be level on nine points with RB Leipzig, the Ukraine side would progress because of their head-to-head record against the Germans in the section.

That follows its 4-1 away win against RB Leipzig on Matchday 1.

The match will take place in Warsaw, Poland because of the war in Ukraine – with the UCL final in Istanbul next June.

Shakhtar Donetsk vs RB Leipzig Odds

Result Moneyline
Shakhtar Donetsk +425
RB Leipzig -165
Draw +330

Odds as of November 1 at DraftKings Sportsbook. Claim this DraftKings Sportsbook promo code before betting on the match.

RB Leipzig is in good form in sixth place in Germany’s Bundesliga and is listed as -165 favorites in the Champions League odds above.

 

 

It is undefeated in five league games with three wins and two draws. Therefore, it is a wide favorite with DraftKings for an away win.

Shakhtar Donetsk is a wide outsider at +425 with the draw at +330. The clash of Shakhtar Donestk vs RB Leipzig kicks off at 1:45 pm ET.

Shakhtar Donetsk vs RB Leipzig Statistics

Shakhtar Donetsk

VS

RB Leipzig

1 Wins 3
3 Draws 0
1 Losses 2
8 Goals 9
6 Goals Against 9
13 Yellow Cards 5
0 Red Cards 0
0 Clean Sheets 1

*Statistics from UCL 2022-23.

In UCL Group F, RB Leipzig has made a good recovery after losing its opening two games.

Following that, it has recorded three straight victories – with an impressive 3-2 defeat of Real Madrid last week at home improving the Germans’ chances of winning the section.

Meanwhile, Shakhtar Donetsk has not won since its opening night defeat of RB Leipzig.

Subsequently, it has drawn three times and lost once – with a 1-1 draw taking place away against Celtic last week ahead of this Shakhtar Donetsk vs RB Leipzig.

Ukraine’s league matches have been taking place in the war-torn country. 

Shakhtar is currently in second place after six wins and two draws so far.

Over/Under & Spread

RB Leipzig has scored an impressive 13 times during the current five-game unbeaten run in the Bundesliga – conceding six times.

It has scored nine times in the UCL but has conceded the same amount.

Shakhtar Donetsk has conceded in every UCL match – but has only allowed in more than one goal on one occasion.

However, both sides will need to be adventurous here with two qualification spots potentially on offer.

So the total goals prop offer for there to be four goals or more looks promising at +155 (Over 3.5).

Among the spread offers, RB Leipzig is priced at +120 to win by two goals (Asian Handicap -1.25).

Meanwhile, underdog Shakhtar Donetsk is rated at +140 simply to win or draw (Asian Handicap +0.5).

Christopher Nkunku to Score Odds

French forward Christopher Nkunku has scored in his last three appearances for RB Leipzig in all competitions.

He has a total of 13 goals this season – and is a decently-priced favorite to score in Shakhtar Donetsk vs RB Leipzig at +125.

Just as attractive are the odds of +350 for Nkunku to be the first or last scorer.

Timo Werner has scored in RB Leipzig’s last two UCL outings and is the second favorite to hit the net in Warsaw at +140. 

He has four Bundesliga goals so far and is priced at +400 to be the first or last scorer in the match.

Lassina Traore is the highest-placed Shakhtar Donestk player among the goalscoring odds in seventh place.

With one goal in five UCL appearances this season, he is priced at +260 to get on the scoresheet in Shakhtar Donetsk vs RB Leipzig.

Shakhtar Donetsk vs RB Leipzig History

The teams have met only once before in Shakhtar Donetsk’s 4-1 win in Leipzig last September.

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Shakhtar Donestk vs RB Leipzig Line-Ups & Injuries

Shakhtar Donestk projected line-up: Trubin – Taylor, Bondar, Matviyenko, Mykhaylichenko – Stepanenko – Bondarenko, Sudakov – Zubkov, Traore, Mudryk

 Shakhtar Donestk Injuries: Shved, Zubkov 

 RB Leipzig projected line-up: Blaswich – Henrichs, Orban (c), Diallo, Raum – Haidara, Schlager – Szoboszlai, Nkunku, Werner – Silva

 RB Leipzig Injuries: Gulacsi, Klostermann, Laimer

Shakhtar Donetsk vs RB Leipzig Prediction

With Christopher Nkunku capitalizing on RB Leipzig’s good form, he is currently in a free-scoring mood. So he looks like a good bet at +125 to get on the scoresheet on Wednesday.

Pick: Christopher Nkunku +125 (To Score)

 

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