Big Ten Championship Prediction: Ohio State vs Indiana Picks & Updated Line

The winner of Ohio State vs Indiana gets the No.1 seed in the CFP Julian Sayin and Fernando Mendoza battle to win the Heisman Continue reading for my Ohio State vs Indiana picks and Big Ten Championship Game prediction The final game before the CFP announcement is one of the...

April 16, 2026 • 6:56 AM

The winner of Ohio State vs Indiana gets the No.1 seed in the CFP

Julian Sayin and Fernando Mendoza battle to win the Heisman

Continue reading for my Ohio State vs Indiana picks and Big Ten Championship Game prediction

The final game before the CFP announcement is one of the best games of recent vintage as the No.2 Indiana Hoosiers and No.1 Ohio State Buckeyes put their 12-0 records on the line to win the Big Ten. Lucas Oil Stadium in Indianapolis will play host to the 8:00 PM ET kickoff on Saturday, Dec. 6. FOX will broadcast the game.

Keep reading for my Ohio State vs Indiana prediction and my Ohio State vs Indiana picks. I also provided the line for the Big Ten Title Game.

Ohio State vs Indiana Prediction for Big Ten Championship Game

Ohio State 24, Indiana 17

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