Final Ole Miss vs Michigan State Odds, Public Betting Splits & Score Projections

The final Ole Miss vs Michigan State odds have moved in favor of the Spartans in the Sweet 16 on Friday Ole Miss has already won two straight games as a plus-money underdog See the closing Ole Miss vs Michigan State odds (spread, total, and moneyline) plus public-betting splits and...

April 16, 2026 • 5:36 AM

The final Ole Miss vs Michigan State odds have moved in favor of the Spartans in the Sweet 16 on Friday

Ole Miss has already won two straight games as a plus-money underdog

See the closing Ole Miss vs Michigan State odds (spread, total, and moneyline) plus public-betting splits and score projections

The #6 Ole Miss Rebels (24-11, 18-16-1 ATS) look to win a third straight March Madness game as underdogs when they square off with the #2 Michigan State Spartans (29-6, 24-10-1 ATS) at State Farm Arena in Atlanta on Friday night at 7:09 pm ET on CBS. The Spartans opened as slight favorites last Sunday and, just hours from tip-off, the Ole Miss vs Michigan State odds have moved in MSU’s favor.

Final Ole Miss vs Michigan State Odds

Bet TypeOle MissMSU
Spread +3.5 (-110) -3.5 (-110)
ML +145 -175
Total O 144.5 (-105) U 144.5 (-115)

Michigan State is now a 3.5-point favorite against the spread and -175 on the moneyline (compared to -162 in the opening line), giving the Spartans a 63.64% implied win probability. The Rebels’ odds to advance have grown from +136 to +145, which carries a 40.82% implied win probability.

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