NFL longshot parlay: Get SportsLine's top Week 4 NFL picks, best bets for shot at huge return

The SportsLine computer simulation model has locked in a 5-leg NFL Week 4 parlay that pays out well over $8k for a $10 bettor

April 16, 2026 • 4:57 AM

The Week 4 NFL schedule is here, and NFL bettors are looking for ways to get the biggest returns. While spread, total and money-line picks remain popular, there's a growing popularity for props, alternate lines with both the spread and total, exact score predictions and other plus-money returns. 

With so many highly-anticipated matchups on the Week 3 NFL schedule like Steelers vs. Vikings (-2.5) in Dublin, a matchup of undefeated teams in Buccaneers vs. Eagles (-3.5), Colts vs. Rams (-3.5), Ravens vs. Chiefs (+2.5), Cowboys vs. Packers (-6.5) on Sunday Night Football, and a doubleheader on Monday Night Football, and parity around the league at an all-time high, finding value in the Week 4 odds can take some extra digging.

Effectively building parlays can pay off big in your NFL betting strategy. Before making your Week 4 NFL picks and parlays, you NEED to see the Week 4 NFL parlay from SportsLine's proven computer simulation model and top-rated experts that could return more than $6,000 for a $10 bettor. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 39-19 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

For Week 4, one of the picks featured in the 5-leg parlay is the Lions, who are listed as -9.5 favorites on the standard spread, covering the alternate spread of -14.5 against the Browns, returning +162. 

The parlay also includes four other picks from the SportsLine computer simulation model, including a first touchdown scorer prop that returns +850! You ABSOLUTELY need to see these picks before locking in any NFL picks of your own.

What are the top NFL picks for Week 4 that can be combined into a parlay that returns well over $8k for $10 bettors? ... Join SportsLine now to see the top NFL picks this week and best bets from SportsLine's proven computer simulation model, and find out!

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